Potato is an essential crop that can play an integral role in achieving global food security. Disease, particularly Late Blight, can be a major issue for farmers often resulting in total crop loss. The United States Agency for International Development (USAID) through the Feed the Future Initiative has awarded a five-year, $13 million award for a collaborative partnership led by Michigan State University (MSU). The Feed the Future Global Biotech Potato Partnership will bring late blight disease resistant (LBR) potatoes in farmer-preferred varieties to the Southeast (SE) Asian countries of Bangladesh and Indonesia, and the Sub-Saharan Africa (SSA) countries of Kenya and Nigeria. This may expand the Activity into other Feed the Future target countries. The Feed the Future Global Biotech Potato Partnership Activity will continue work of previous USAID investments focused on the research and development of the LBR potato through genetic engineering. The Global Biotech Potato Partnership is a collaboration between MSU, the International Potato Center (CIP), the University of Minnesota, the University of Idaho, African Agricultural Technology Foundation (AATF), and partner country National Agricultural Research Systems (NARS). Building the capacity of the NARS, to conduct this research in the four countries is also a primary goal of the project. The partnership will utilize cutting-edge research to promote a robust potato value chain through the commercialization of the 3 R-gene Late Blight Resistant (LBR) potato as well as developing 2nd generation disease resistant potato products. The goal is to sustainably reduce global poverty, hunger, and malnutrition. This will ultimately help emerging economies in SE Asia and SSA countries accelerate progress towards self-reliance. The Global Biotechnology Potato Partnership expects to complete required research necessary to receive regulatory approvals for general release and commercialization of the LBR potato in each of the four target countries within the next five years.